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2015 | OriginalPaper | Buchkapitel

21. Schmerztherapie bei lebensbedrohlichen und lebenslimitierenden Erkrankungen

verfasst von : Prof. Dr. med. Boris Zernikow, Dr. med. Carola Hasan

Erschienen in: Schmerztherapie bei Kindern, Jugendlichen und jungen Erwachsenen

Verlag: Springer Berlin Heidelberg

Zusammenfassung

In den europäischen Ländern nehmen lebenslimitierende Erkrankungen im Kindes- und Jugendalter zu. Die Beurteilung und Therapie der Schmerzen sollte auf Basis des Total Pain Concepts geschehen und physische, psychische, soziale sowie spirituelle Aspekte berücksichtigen. Die Schmerzerfassung ist bei nicht-verbal kommunizierenden Patienten mit schwerer Mehrfachbehinderung eine besondere Herausforderung. Bei Nozizeptorschmerzen sollten Opioide und Nicht-Opioide kombiniert werden, wie dies das WHO Stufenschema beschreibt. Retardiertes Morphin in Granulatform ist für Kinder besonders geeignet. Adjuvanzien kommen bei neuropathischen Schmerzen zum Einsatz. Es sollte die am wenigsten invasive Applikationsform gewählt werden. Die Medikamentendosierung erfolgt auf Basis des Körpergewichts. Neurologisch kranke Kinder reagieren besonders sensibel auf starke Opioide, so dass eine Dosisanpassung nach unten erfolgen muss. Mögliche Nebenwirkungen der Analgetikatherapie müssen antizipiert werden. Die PCA ist eine wichtige Therapieoption, auch bei der häuslichen Versorgung.
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Zurück zum Zitat Zernikow B, Schiessl C, Wamsler C, Grießinger N, Sittl R (2005b) Opioidtherapie chronischer Schmerzen bei Kindern – Fallbesprechungen. Schmerz 19: 418–425 Zernikow B, Schiessl C, Wamsler C, Grießinger N, Sittl R (2005b) Opioidtherapie chronischer Schmerzen bei Kindern – Fallbesprechungen. Schmerz 19: 418–425
Zurück zum Zitat Zernikow B, Smale H, Michel E, Hasan C, Jorch N, Andler W (2006) Paediatric cancer pain management using the WHO analgesic ladder – Results of a prospective analysis from 2265 treatment days during a quality improvement study. Eur J Pain 10: 587–595PubMed Zernikow B, Smale H, Michel E, Hasan C, Jorch N, Andler W (2006) Paediatric cancer pain management using the WHO analgesic ladder – Results of a prospective analysis from 2265 treatment days during a quality improvement study. Eur J Pain 10: 587–595PubMed
Zurück zum Zitat Zernikow B, Michel E, Anderson BJ (2007) Transdermal fentanyl in childhood and adolescence: a comprehensive literature review. J Pain 8: 187–207PubMed Zernikow B, Michel E, Anderson BJ (2007) Transdermal fentanyl in childhood and adolescence: a comprehensive literature review. J Pain 8: 187–207PubMed
Zurück zum Zitat Zernikow B, Michel E, Craig F, Anderson BJ (2009) Pediatric palliative care: Use of opioids for the management of pain. Pediatr Drugs 11: 129–151 Zernikow B, Michel E, Craig F, Anderson BJ (2009) Pediatric palliative care: Use of opioids for the management of pain. Pediatr Drugs 11: 129–151
Metadaten
Titel
Schmerztherapie bei lebensbedrohlichen und lebenslimitierenden Erkrankungen
verfasst von
Prof. Dr. med. Boris Zernikow
Dr. med. Carola Hasan
Copyright-Jahr
2015
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-45057-4_21

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